CD9-mediated activation of the p46 Shc isoform leads to apoptosis in cancer cells

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چکیده

منابع مشابه

CD9-mediated activation of the p46 Shc isoform leads to apoptosis in cancer cells.

CD9, a member of the tetraspanin family, has been shown to be involved in a range of cellular activities, including migration, proliferation and adhesion, but the molecular mechanisms by which it mediates such events is unclear. Here, we found that anti-CD9 monoclonal antibody ALB6 inhibited cell proliferation, reduced cell viability and induced not only morphological changes specific to apopto...

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The analysis and functional characterization of ectopically expressed human olfactory receptors (ORs) is becoming increasingly important, as many ORs have been identified in several healthy and cancerous tissues. OR activation has been demonstrated to have influence on cancer cell growth and progression. Here, ORs were identified using RNA-Seq analyses and RT-PCR. We demonstrated the OR protein...

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from linguistics to literature: a linguistic approach to the study of linguistic deviations in the turkish divan of shahriar

chapter i provides an overview of structural linguistics and touches upon the saussurean dichotomies with the final goal of exploring their relevance to the stylistic studies of literature. to provide evidence for the singificance of the study, chapter ii deals with the controversial issue of linguistics and literature, and presents opposing views which, at the same time, have been central to t...

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Rottlerin-induced autophagy leads to apoptosis in bladder cancer cells

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the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

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ژورنال

عنوان ژورنال: Journal of Cell Science

سال: 2004

ISSN: 1477-9137,0021-9533

DOI: 10.1242/jcs.01201